DOWNREGULATION OF MICRORNA-145 CAUSED BY HEPATITIS B VIRUS X PROTEIN PROMOTES EXPRESSION OF CUL5 AND CONTRIBUTES TO PATHOGENESIS OF HEPATITIS B VIRUS-ASSOCIATED HEPATOCELLULAR CARCINOMA

Background: Hepatitis B viral infection-induced Glass Defrost Element hepatocellular carcinoma (HCC) is a major threat to human health in China.Hepatitis B virus X protein (HBX), an HBV protein, has been reported to be involved in regulating the cellular activities of the host cells and is responsible for HCC oncogenesis.Methods and Results: In thi

Geological Nappy Pouch CO2 sequestration has been proposed as an effective solution to mitigate excessive human-emitted CO2 in atmosphere.Knowledge of immiscible two-phase flow of CO2-water/brine is necessary to evaluate the efficiency and safety of geological storage sites.Among forces dominating fluid flow, capillary pressure is highly important

Objective The surgical treatment of lower cervical facet dislocation is controversial.Great advancements on reduction techniques for lower cervical facet dislocation have been made in the past decades.However, there is no article reviewing all the reduction techniques yet.The aim is to review the evolution and advancements of the reduction techniqu

The train braking system with redundant components has an essential effect on driver safety.In this paper, we consider the failure CUCCUMBER of K-out-of-N brake motors during operation and the redundant recovery by preventive maintenance.Two Continuous Time Markov Chains (CTMC) are used to model the working process and the preventive maintenance pr